Profile of Se-Jin Lee

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Profile of Xiang-Jin Meng.

Trained in both human medical and veterinary sciences, Xiang-Jin Meng has made numerous contributions to the field of comparative viral pathogenesis. His achievements concerning emerging, reemerging, and zoonotic viral diseases include the discovery of swine and avian hepatitis E viruses (HEV) and the invention of a commercial vaccine against porcine circovirus type 2 (PCV2), a common pathogen ...

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Activation of Autophagy Rescues Amiodarone-Induced Apoptosis of Lung Epithelial Cells and Pulmonary Toxicity in Rats Kang-Yo Lee,* Sehee Oh,* You-Jin Choi,* Seon-Hee Oh,† Young-Su Yang,‡ Mi-Jin Yang,‡ Kyuhong Lee,‡ and Byung-Hoon Lee*

Amiodarone, bi-iodinated benzofuran derivative, is one of the most frequently prescribed and efficacious antiarrhythmic drugs. Despite its low incidence, amiodarone-induced pulmonary toxicity is of great concern and the leading cause of discontinuation. Autophagy is an essential homeostatic process that mediates continuous recycling of intracellular materials when nutrients are scarce. It eithe...

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Na - Young Yang , Yu - Na Lee , He - Jin Lee , Yoon Suk Kim and Seung - Jae Lee * Glucocerebrosidase , a new player changing the old rules in Lewy body diseases

Mutations in the gene encoding glucocerebrosidase ( GBA1 ) cause Gaucher disease (GD), a lysosomal storage disease with recessive inheritance. Glucocerebrosidase (GCase) is a lysosomal lipid hydrolase that digests glycolipid substrates, such as glucosylceramide and glucosylsphingosine. GBA1 mutations have been implicated in Lewy body diseases (LBDs), such as Parkinson ’ s disease and dementia w...

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Yang–Lee zeros of the Yang–Lee model

To understand the distribution of the Yang–Lee zeros in quantum integrable field theories we analyse the simplest of these systems given by the 2D Yang– Lee model. The grand-canonical partition function of this quantum field theory, as a function of the fugacity z and the inverse temperature β, can be computed in terms of the thermodynamics Bethe Ansatz based on its exact S-matrix. We extract t...

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Stability of Jin-xin Relaxation Shocks

We examine the spectrum of shock profiles for the Jin-Xin relaxation scheme for systems of hyperbolic conservation laws in one spatial dimension. By using a weighted norm estimate, we prove that these shock profiles exhibit strong spectral stability in the weak shock limit.

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2020

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.2023335117